Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression

Estrogen promotes estrogen receptor negative BRCA1-deficient tumor initiation and progression

Abstract Background Estrogen promotes breast cancer development and progression mainly through estrogen receptor (ER). However, blockage of estrogen production or action prevents development of and suppresses progression of ER-negative breast cancers. How estrogen promotes ER-negative breast cancer...

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Bibliographic Details
Main Authors: Chuying Wang, Feng Bai, Li-han Zhang, Alexandria Scott, Enxiao Li, Xin-Hai Pei
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Breast Cancer Research
Subjects:
Estrogen
Estrogen receptor
BRCA1
EMT
Cancer stem cells
Online Access:http://link.springer.com/article/10.1186/s13058-018-0996-9

Internet

http://link.springer.com/article/10.1186/s13058-018-0996-9

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