Restoring Prohealing/Remodeling-Associated M2a/c Macrophages Using ON101 Accelerates Diabetic Wound Healing

Restoring Prohealing/Remodeling-Associated M2a/c Macrophages Using ON101 Accelerates Diabetic Wound Healing

Diabetic wounds exhibit chronic inflammation and delayed tissue proliferation or remodeling, mainly owing to prolonged proinflammatory (M1) macrophage activity and defects in transition to prohealing/proremodeling (M2a/M2c; CD206+ and/or CD163+) macrophages. We found that topical treatment with ON10...

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Bibliographic Details
Main Authors: Ching-Wen Lin, Chih-Chiang Chen, Wen-Yen Huang, Yen-Yu Chen, Shiou-Ting Chen, Hung-Wen Chou, Chien-Ming Hung, Wan-Jiun Chen, Chia-Sing Lu, Shi-Xin Nian, Shyi-Gen Chen, Hsuen-Wen Chang, Vincent H.S. Chang, Li-Ying Liu, Ming-Liang Kuo, Shun-Cheng Chang
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:JID Innovations
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026722000467

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http://www.sciencedirect.com/science/article/pii/S2667026722000467

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