Maternal Folic Acid Intake and Methylation Status of Genes Associated with Ventricular Septal Defects in Children: Case–Control Study

Maternal Folic Acid Intake and Methylation Status of Genes Associated with Ventricular Septal Defects in Children: Case–Control Study

Background: DNA methylation is the best epigenetic mechanism for explaining the interactions between nutrients and genes involved in intrauterine growth and development programming. A possible contributor of methylation abnormalities to congenital heart disease is the folate methylation regulatory p...

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Bibliographic Details
Main Authors: Sandra M. González-Peña, Geovana Calvo-Anguiano, Laura E. Martínez-de-Villarreal, Patricia R. Ancer-Rodríguez, José J. Lugo-Trampe, Donato Saldivar-Rodríguez, María D. Hernández-Almaguer, Melissa Calzada-Dávila, Ligia S. Guerrero-Orjuela, Luis D. Campos-Acevedo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nutrients
Subjects:
folic acid intake
ventricular septal defects
congenital heart disease
methylation status
<i>AXIN1</i>
<i>MTHFR</i>
Online Access:https://www.mdpi.com/2072-6643/13/6/2071

Internet

https://www.mdpi.com/2072-6643/13/6/2071

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