Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis

Sputum from patients with primary ciliary dyskinesia contains high numbers of dysfunctional neutrophils and inhibits efferocytosis

Abstract Background Primary ciliary dyskinesia (PCD) is a genetic disorder characterized by recurrent airway infection and inflammation. There is no cure for PCD and to date there are no specific treatments available. Neutrophils are a crucial part of the immune system and are known to be dysfunctio...

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Bibliographic Details
Main Authors: Marfa Blanter, Maaike Cockx, Liesel Wittebols, Sara Abouelasrar Salama, Mirre De Bondt, Nele Berghmans, Noëmie Pörtner, Lotte Vanbrabant, Natalie Lorent, Mieke Gouwy, Mieke Boon, Sofie Struyf
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Respiratory Research
Subjects:
Primary ciliary dyskinesia
Neutrophil
Airway
Inflammation
Bronchiectasis
Sputum
Online Access:https://doi.org/10.1186/s12931-022-02280-7

Internet

https://doi.org/10.1186/s12931-022-02280-7

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