Mechanical Cues, E-Cadherin Expression and Cell “Sociality” Are Crucial Crossroads in Determining Pancreatic Ductal Adenocarcinoma Cells Behavior

Mechanical Cues, E-Cadherin Expression and Cell “Sociality” Are Crucial Crossroads in Determining Pancreatic Ductal Adenocarcinoma Cells Behavior

E-cadherin, an epithelial-to-mesenchymal transition (EMT) marker, is coupled to actin cytoskeleton and distributes cell forces acting on cells. Since YAP transduces mechanical signals involving actin cytoskeleton, we aimed to investigate the relationship between YAP and mechanical cues in pancreatic...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Francesca Bianchi, Michele Sommariva, Laura Brigida Cornaghi, Luca Denti, Ambra Nava, Francesca Arnaboldi, Claudia Moscheni, Nicoletta Gagliano
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: MDPI AG 2022-04-01
Цуврал:Cells
Нөхцлүүд:
pancreatic cancer
3D spheroids
actin cytoskeleton
E-cadherin
epithelial-to-mesenchymal transition
MMPs
Онлайн хандалт:https://www.mdpi.com/2073-4409/11/8/1318

Интернэт

https://www.mdpi.com/2073-4409/11/8/1318

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