Short-course eflornithine in Gambian trypanosomiasis: a multicentre randomized controlled trial

Short-course eflornithine in Gambian trypanosomiasis: a multicentre randomized controlled trial

OBJECTIVE: A randomized controlled trial was conducted to determine whether 7 days of intravenous eflornithine (100 mg/kg every 6 h) was as effective as the standard 14-day regimen in the treatment of late-stage Trypanosoma brucei gambiense trypanosomiasis. METHODS: A total of 321 patients (274 new...

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Bibliographic Details
Main Authors: Jacques Pépin, Nzambi Khonde, Faustine Maiso, Félix Doua, Shabbar Jaffar, Stéphane Ngampo, Bokelo Mpia, Dawson Mbulamberi, Felix Kuzoe
Format: Article
Language:English
Published: The World Health Organization 2000-11-01
Series:Bulletin of the World Health Organization
Subjects:
trypanosomiasis
Trypanosoma brucei gambiense
eflornithine
eflorithine
trypanocidal agents
randomized controlled trials
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862000001100003&lng=en&tlng=en

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http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862000001100003&lng=en&tlng=en

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