Genomic alterations and possible druggable mutations in carcinoma of unknown primary (CUP)

Abstract Carcinoma of Unknown Primary (CUP) is a heterogeneous and metastatic disease where the primary site of origin is undetectable. Currently, chemotherapy is the only state-of-art treatment option for CUP patients. The molecular profiling of the tumour, particularly mutation detection, offers a...

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Bibliographic Details
Main Authors: Hamidreza Aboulkheyr Es, Hamid Mahdizadeh, Amir Abbas Hedayati Asl, Mehdi Totonchi
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94678-4