LaRA 2: parallel and vectorized program for sequence–structure alignment of RNA sequences

LaRA 2: parallel and vectorized program for sequence–structure alignment of RNA sequences

Abstract Background The function of non-coding RNA sequences is largely determined by their spatial conformation, namely the secondary structure of the molecule, formed by Watson–Crick interactions between nucleotides. Hence, modern RNA alignment algorithms routinely take structural information into...

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Bibliographic Details
Main Authors: Jörg Winkler, Gianvito Urgese, Elisa Ficarra, Knut Reinert
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Bioinformatics
Subjects:
RNA secondary structure
Integer linear program
Bioinformatics
Structural alignment
RNA
Algorithms
Online Access:https://doi.org/10.1186/s12859-021-04532-7

Internet

https://doi.org/10.1186/s12859-021-04532-7

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