LaRA 2: parallel and vectorized program for sequence–structure alignment of RNA sequences

Abstract Background The function of non-coding RNA sequences is largely determined by their spatial conformation, namely the secondary structure of the molecule, formed by Watson–Crick interactions between nucleotides. Hence, modern RNA alignment algorithms routinely take structural information into...

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Detalles Bibliográficos
Main Authors: Jörg Winkler, Gianvito Urgese, Elisa Ficarra, Knut Reinert
Formato: Artigo
Idioma:English
Publicado: BMC 2022-01-01
Series:BMC Bioinformatics
Subjects:
Acceso en liña:https://doi.org/10.1186/s12859-021-04532-7