Generation of anti-TLR2 intrabody mediating inhibition of macrophage surface TLR2 expression and TLR2-driven cell activation

<p>Abstract</p> <p>Background</p> <p>Toll-like receptor (TLR) 2 is a component of the innate immune system and senses specific pathogen associated molecular patterns (PAMPs) of both microbial and viral origin. Cell activation via TLR2 and other pattern recognition recep...

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Bibliographic Details
Main Authors: Lindenmaier Werner, Noack Andreas, Köster Mario, Schade Jutta, Fichte Sylvia, Maaß Björn, Dreher Stefan, Kirschning Carsten J, Wagner Hermann, Böldicke Thomas
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/10/31