The mechanism underlying transient weakness in myotonia congenita

The mechanism underlying transient weakness in myotonia congenita

In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed intracellular recordings from muscle of both genetic and pharmacologic mous...

Podrobná bibliografie
Hlavní autoři:	Jessica H Myers, Kirsten Denman, Chris DuPont, Ahmed A Hawash, Kevin R Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A Voss, Mark M Rich
Médium:	Článek
Jazyk:	English
Vydáno:	eLife Sciences Publications Ltd 2021-04-01
Edice:	eLife
Témata:	muscle fiber myotonia sodium channel calcium channel persistent sodium current excitability
On-line přístup:	https://elifesciences.org/articles/65691

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