The mechanism underlying transient weakness in myotonia congenita

The mechanism underlying transient weakness in myotonia congenita

In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed intracellular recordings from muscle of both genetic and pharmacologic mous...

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Detalhes bibliográficos
Main Authors:	Jessica H Myers, Kirsten Denman, Chris DuPont, Ahmed A Hawash, Kevin R Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A Voss, Mark M Rich
Formato:	Artigo
Idioma:	English
Publicado em:	eLife Sciences Publications Ltd 2021-04-01
Colecção:	eLife
Assuntos:	muscle fiber myotonia sodium channel calcium channel persistent sodium current excitability
Acesso em linha:	https://elifesciences.org/articles/65691

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