Effect of specific silencing HIF-1α on expression of Vimentin in OCM-1 cells under hypoxia

AIM:To investigate the effect of specific silencing hypoxia inducible factor-1 alpha(HIF-1α)by small interference RNA(siRNA)on expression of vimentin in human uveal melanoma cell lines(OCM-1)under hypoxia, in order to discuss the role of HIF-1α on epithelial-mesenchymal transition(EMT)in uveal melan...

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Bibliographic Details
Main Authors: Juan Zhao, Zhan-Yu Zhou, Shuang Wang, Fu-Xiang Yuan, Fa-Yan Lu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2014-03-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://www.ies.net.cn/cn_publish/2014/3/201403008.pdf