Molecular mechanism of cyclodextrin mediated cholesterol extraction.

The depletion of cholesterol from membranes, mediated by β-cyclodextrin (β-CD) is well known and documented, but the molecular details of this process are largely unknown. Using molecular dynamics simulations, we have been able to study the CD mediated extraction of cholesterol from model membranes,...

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Bibliographic Details
Main Authors: Cesar A López, Alex H de Vries, Siewert J Marrink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3063748?pdf=render