Effects of the angiotensin-converting enzyme inhibitor captopril on occlusal-disharmony-induced cardiac dysfunction in mice

Abstract Occlusal disharmony is known to affect not only the oral cavity environment, but also the autonomic nervous system in the heart. Since the renin-angiotensin system (RAS) inhibitor captopril (Cap) is one of the first-line drugs for preventing cardiac remodeling in patients with heart failure...

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Bibliographic Details
Main Authors: Aiko Ito, Yoshiki Ohnuki, Kenji Suita, Ichiro Matsuo, Misao Ishikawa, Takao Mitsubayashi, Yasumasa Mototani, Kenichi Kiyomoto, Michinori Tsunoda, Akinaka Morii, Megumi Nariyama, Yoshio Hayakawa, Hiroshi Tomonari, Satoshi Okumura
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43099-6