Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases

Porphyromonas gingivalis is a major pathogenic bacterium involved in the pathogenesis of periodontitis. Citrullination has been reported as the underlying mechanism of the pathogenesis, which relies on the interplay between two virulence factors of the bacterium, namely gingipain R and the bacterial...

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Bibliographic Details
Main Authors: Yoke Chan Chow, Hok Chai Yam, Baskaran Gunasekaran, Weng Yeen Lai, Weng Yue Wo, Tarun Agarwal, Yien Yien Ong, Siew Lee Cheong, Sheri-Ann Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.987683/full