Evaluation of mitochondrial biogenesis and ROS generation in high-grade serous ovarian cancer

Evaluation of mitochondrial biogenesis and ROS generation in high-grade serous ovarian cancer

IntroductionOvarian cancer is one of the leading causes of death for women with cancer worldwide. Energy requirements for tumor growth in epithelial high-grade serous ovarian cancer (HGSOC) are fulfilled by a combination of aerobic glycolysis and oxidative phosphorylation (OXPHOS). Although reduced...

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Bibliographic Details
Main Authors: Zeynep C. Koc, Vincent E. Sollars, Nadim Bou Zgheib, Gary O. Rankin, Emine C. Koc
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
mitochondrial biogenesis
mitochondrial translation and transcription
mitochondrial reactive oxygen species (mtROS)
oxidative phosphorylation (OXPHOS)
high-grade serous ovarian cancer (HGSOC)
MT-COII
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1129352/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1129352/full

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