Comparative Assessment of In Vitro and In Silico Methods for Aerodynamic Characterization of Powders for Inhalation

Comparative Assessment of In Vitro and In Silico Methods for Aerodynamic Characterization of Powders for Inhalation

In vitro assessment of dry powders for inhalation (DPIs) aerodynamic performance is an inevitable test in DPI development. However, contemporary trends in drug development also implicate the use of in silico methods, e.g., computational fluid dynamics (CFD) coupled with discrete phase modeling (DPM)...

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Bibliographic Details
Main Authors: Jelisaveta Ignjatović, Tijana Šušteršič, Aleksandar Bodić, Sandra Cvijić, Jelena Đuriš, Alessandra Rossi, Vladimir Dobričić, Svetlana Ibrić, Nenad Filipović
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
dry powders for inhalation (DPIs)
computational fluid dynamics (CFD)
discrete phase modeling (DPM)
aerodynamic performance
solid lipid microparticles
Online Access:https://www.mdpi.com/1999-4923/13/11/1831

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https://www.mdpi.com/1999-4923/13/11/1831

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