MiR-181a Targets RSPO2 and Regulates Bone Morphogenetic Protein – WNT Signaling Crosstalk During Chondrogenic Differentiation of Mesenchymal Stromal Cells

MiR-181a Targets RSPO2 and Regulates Bone Morphogenetic Protein – WNT Signaling Crosstalk During Chondrogenic Differentiation of Mesenchymal Stromal Cells

Mechanisms of WNT and bone morphogenetic protein (BMP) signaling crosstalk is in the focus of multiple biological studies, and it also has been discovered to play important roles in human mesenchymal stromal cells (MSC) that are of great interest for neocartilage engineering due to their high chondr...

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Bibliographic Details
Main Authors: Svitlana Melnik, Nina Hofmann, Jessica Gabler, Nicole Hecht, Wiltrud Richter
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
miR-181a
mesenchymal stromal cells (MSC)
chondrogenesis
osteoarthritis (OA)
RSPO2
WNT signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.747057/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.747057/full

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