Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity

Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity

<p>Abstract</p> <p>Background</p> <p>Proteolytic enzymes have been implicated in driving tumor progression by means of their cancer cell microenvironment activity where they promote proliferation, differentiation, apoptosis, migration, and invasion. Therapeutic strategi...

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Main Authors: Kwok Hang Fai, Buick Richard J, Kuehn Diana, Gormley Julie A, Doherty Declan, Jaquin Thomas J, McClurg Angela, Ward Claire, Byrne Teresa, Jaworski Jacob, Leung Ka Lai, Snoddy Philip, McAnally Christine, Burden Roberta E, Gray Breena, Lowry Jenny, Sermadiras Isabelle, Gruszka Natalia, Courtenay-Luck Nigel, Kissenpfennig Adrien, Scott Christopher J, Johnston James A, Olwill Shane A
格式: Article
語言:English
出版: BMC 2011-12-01
叢編:Molecular Cancer
主題:
Cathepsin S
ADCC
antibody
protease
microenvironment
在線閱讀:http://www.molecular-cancer.com/content/10/1/147

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http://www.molecular-cancer.com/content/10/1/147

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