Cytochrome P450 Expression and Chemical Metabolic Activity before Full Liver Development in Zebrafish

Cytochrome P450 Expression and Chemical Metabolic Activity before Full Liver Development in Zebrafish

Zebrafish are used widely in biomedical, toxicological, and developmental research, but information on their xenobiotic metabolism is limited. Here, we characterized the expression of 14 xenobiotic cytochrome P450 (CYP) subtypes in whole embryos and larvae of zebrafish (4 to 144 h post-fertilization...

Full description

Bibliographic Details
Main Authors: Tasuku Nawaji, Natsumi Yamashita, Haruka Umeda, Shuangyi Zhang, Naohiro Mizoguchi, Masanori Seki, Takio Kitazawa, Hiroki Teraoka
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Pharmaceuticals
Subjects:
cytochrome P450
drug metabolism
developing zebrafish
Online Access:https://www.mdpi.com/1424-8247/13/12/456

Internet

https://www.mdpi.com/1424-8247/13/12/456

Similar Items