Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1–11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial

Testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1–11-month-old infants in Mali (LAKANA): study protocol for a cluster-randomized, placebo-controlled, double-blinded, parallel-group, three-arm clinical trial

Abstract Background Mass drug administration (MDA) of azithromycin (AZI) has been shown to reduce under-5 mortality in some but not all sub-Saharan African settings. A large-scale cluster-randomized trial conducted in Malawi, Niger, and Tanzania suggested that the effect differs by country, may be s...

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Bibliographic Details
Main Authors: Laura Adubra, Dagmar Alber, Per Ashorn, Ulla Ashorn, Yin Bun Cheung, Elaine Cloutman-Green, Fatoumata Diallo, Camilla Ducker, Riku Elovainio, Yue-Mei Fan, Lily Gates, Gwydion Gruffudd, Tiia Haapaniemi, Fadima Haidara, Lotta Hallamaa, Rikhard Ihamuotila, Nigel Klein, Juho Luoma, Owen Martell, Samba Sow, Taru Vehmasto, LAKANA Trial Team
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Trials
Subjects:
Randomized controlled trial
Infant
Antibiotic
Azithromycin
Placebo
Mortality
Online Access:https://doi.org/10.1186/s13063-022-06966-7

Internet

https://doi.org/10.1186/s13063-022-06966-7

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