Zero-preserving imputation of single-cell RNA-seq data
Missing values in scRNA-seq datasets can bias their analysis. Here, the authors threshold the low rank approximation of the expression matrix, so false zeros can be imputed while true zeros are preserved.
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-27729-z |