Diagnostic value of kappa free light chain index in patients with primary progressive multiple sclerosis – a multicentre study

Diagnostic value of kappa free light chain index in patients with primary progressive multiple sclerosis – a multicentre study

BackgroundKappa free light chains (κ-FLC) in the cerebrospinal fluid (CSF) are an emerging biomarker in multiple sclerosis (MS).ObjectiveTo investigate whether κ-FLC index has similar diagnostic value in patients with primary progressive multiple sclerosis (PPMS) compared to oligoclonal bands (OCB)....

Full description

Bibliographic Details
Main Authors: Harald Hegen, Klaus Berek, Paola Cavalla, Mikael Christiansen, Andreja Emeršič, Massimiliano Di Filippo, Lorenzo Gaetani, Michaela Hassler, Cyra Leurs, Dejan Milosavljevic, Vincent van Pesch, Thor Petersen, Stefan Presslauer, Igal Rosenstein, Uroš Rot, Christine Schnabl, Charlotte Teunissen, Domizia Vecchio, Marco Vercellino, Florian Deisenhammer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
cerebrospinal fluid
kappa free light chain
primary progressive
multiple sclerosis
diagnosis
sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1327947/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1327947/full

Similar Items