Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson’s disease
Abstract Iron accumulates gradually in the ageing brain. In Parkinson’s disease, iron deposition within the substantia nigra is further increased, contributing to a heightened pro-oxidant environment in dopaminergic neurons. We hypothesise that individuals in high-income countries, where cereals and...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-01-01
|
Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-016-0004-y |