Molecular screening for the mutation associated with canine degenerative myelopathy (SOD1:c.118G > A) in German Shepherd dogs in Brazil.

Canine Degenerative Myelopathy is a late onset recessive autosomal disease characterized by a progressive ascending degeneration of the spinal cord. Two causal mutations are associated with this disease: a transition (c.118G>A) in exon 2 of the SOD1 that was described in several breeds and a tran...

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Main Authors: Cássia Regina Oliveira Santos, João José de Simoni Gouveia, Gisele Veneroni Gouveia, Flávia Caroline Moreira Bezerra, Joel Fonseca Nogueira, Durval Baraúna Júnior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242347