DNA repair deficiency as circulating biomarker in prostate cancer

DNA repair deficiency as circulating biomarker in prostate cancer

Deleterious aberrations in DNA repair genes are actionable in approximately 25% of metastatic castration-resistant prostate cancers (mCRPC) patients. Homology recombination repair (HRR) is the DNA damage repair (DDR) mechanism most frequently altered in prostate cancer; of note BRCA2 is the most fre...

Full description

Bibliographic Details
Main Authors: Martina Catalano, Daniele Generali, Marta Gatti, Barbara Riboli, Leda Paganini, Gabriella Nesi, Giandomenico Roviello
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
DNA damage repair
prostate cancer
liquid biopsy
circulating biomarker
circulating tumor DNA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1115241/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1115241/full

Similar Items