GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus

GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus

ABSTRACTInterferons (IFNs) control viral infections by inducing expression of IFN-stimulated genes (ISGs) that restrict distinct steps of viral replication. We report herein that gamma-interferon-inducible lysosomal thiol reductase (GILT), a lysosome-associated ISG, restricts the infectious entry of...

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Bibliographic Details
Main Authors: Danying Chen, Zhifei Hou, Dong Jiang, Mei Zheng, Guoli Li, Yue Zhang, Rui Li, Hanxin Lin, Jinhong Chang, Hui Zeng, Ju-Tao Guo, Xuesen Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Emerging Microbes and Infections
Subjects:
Interferon-stimulated genes (ISGs)
GILT
SARS-CoV
Ebola virus
Lassa fever virus
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2019.1677446

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https://www.tandfonline.com/doi/10.1080/22221751.2019.1677446

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