A Glutamatergic Spine Model to Enable Multi-Scale Modeling of Nonlinear Calcium Dynamics
In synapses, calcium is required for modulating synaptic transmission, plasticity, synaptogenesis, and synaptic pruning. The regulation of calcium dynamics within neurons involves cellular mechanisms such as synaptically activated channels and pumps, calcium buffers, and calcium sequestrating organe...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-07-01
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Series: | Frontiers in Computational Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fncom.2018.00058/full |