Replication and Spread of Oncolytic Herpes Simplex Virus in Solid Tumors

Oncolytic herpes simplex virus (oHSV) is a highly promising treatment for solid tumors. Intense research and development efforts have led to first-in-class approval for an oHSV for melanoma, but barriers to this promising therapy still exist that limit efficacy. The process of infection, replication...

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Bibliographic Details
Main Authors: Bangxing Hong, Upasana Sahu, Matthew P. Mullarkey, Balveen Kaur
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/1/118