Pretreatment with Chrysin Reduces Ifosfamide-Induced Acute Nephrotoxicity in Male Rats through Mitochondrial Protection

Background: Ifosfamide-induced kidney damage is an important toxicity in children and adults undergoing chemotherapy. Studies have previously demonstrated that toxic metabolites of ifosfamide, such as acrolein, are associated with depletion of antioxidants, oxidative stress, and mitochondrial impair...

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Bibliographic Details
Main Authors: Ahmad Salimi, Zhaleh Jamali, Mohammad Shabani, Deniz Bayrami, Amin Ashena Moghadam
Format: Article
Language:fas
Published: Ardabil University of Medical Sciences 2024-10-01
Series:Journal of Ardabil University of Medical Sciences
Subjects:
Online Access:http://jarums.arums.ac.ir/article-1-2457-en.pdf