Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer

Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer

Endocrine therapy is the mainstay of adjuvant treatment for patients with luminal breast cancer. Despite ongoing advances in endocrine therapy to date, a proportion of patients ultimately develop endocrine resistance, resulting in failure of therapy and poor prognosis. Therefore, as part of the grow...

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Bibliographic Details
Main Authors: Lutfi H. Alfarsi, Rokaya El Ansari, Brendah K. Masisi, Ruth Parks, Omar J Mohammed, Ian O. Ellis, Emad A. Rakha, Andrew R. Green
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
DBN1
oestrogen receptor
breast cancer
endocrine resistance
predictive biomarker
Online Access:https://www.mdpi.com/2072-6694/12/6/1549

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https://www.mdpi.com/2072-6694/12/6/1549

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