Rapid and accurate multiple testing correction and power estimation for millions of correlated markers.

With the development of high-throughput sequencing and genotyping technologies, the number of markers collected in genetic association studies is growing rapidly, increasing the importance of methods for correcting for multiple hypothesis testing. The permutation test is widely considered the gold s...

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Bibliographic Details
Main Authors: Buhm Han, Hyun Min Kang, Eleazar Eskin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2663787?pdf=render