Upregulation of Peptide Transporters PEPT1 and PEPT2 by Janus Kinase JAK2

Upregulation of Peptide Transporters PEPT1 and PEPT2 by Janus Kinase JAK2

Background/Aims: Janus-activated kinase-2 JAK2 participates in the signaling of several hormones including growth hormone, fosters tumor growth and modifies the activity of several Na+ coupled nutrient transporters. Peptide uptake into intestinal and tumor cells is accomplished by electrogenic pepti...

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Bibliographic Details
Main Authors: Zohreh Hosseinzadeh, Luo Dong, Shefalee K. Bhavsar, Jamshed Warsi, Ahmad Almilaji, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Peptide transport
Nutrient transport
Intestine
JAK2 inhibitor AG490
Energy depletion
Online Access:http://www.karger.com/Article/FullText/350086

Internet

http://www.karger.com/Article/FullText/350086

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