Regulation of I<sub>Ks</sub> Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase

Regulation of I<sub>Ks</sub> Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase

The subunits KCNQ1 and KCNE1 generate the slowly activating, delayed rectifier potassium current, I<sub>Ks</sub>, that responds to sympathetic stimulation and is critical for human cardiac repolarization. The A-kinase anchoring protein Yotiao facilitates macromolecular complex formation...

Full description

Bibliographic Details
Main Authors: Yong Li, Thomas Hof, Tanya A. Baldwin, Lei Chen, Robert S. Kass, Carmen W. Dessauer
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cells
Subjects:
adenylyl cyclase
AC9
A-kinase anchoring protein
AKAP
cyclic AMP
cardiomyocyte
Yotiao
KCNQ1
protein kinase A
potassium channels
Online Access:https://www.mdpi.com/2073-4409/8/9/981

Internet

https://www.mdpi.com/2073-4409/8/9/981

Similar Items