An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage

An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage

Abstract Ultraviolet radiation (UVR) induces immunosuppression and DNA damage, both of which contribute to the rising global incidence of skin cancer including melanoma. Nucleotide excision repair, which is activated upon UVR-induced DNA damage, is linked to expression of interleukin-12 (IL-12) whic...

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Bibliographic Details
Main Authors: Michael Agrez, Mark Stephen Rybchyn, Warusavithana Gunawardena Manori De Silva, Rebecca Sara Mason, Christopher Chandler, Terrence J. Piva, Kristofer Thurecht, Nicholas Fletcher, Feifei Liu, Gayathri Subramaniam, Christopher B. Howard, Benjamin Blyth, Stephen Parker, Darryl Turner, Justyna Rzepecka, Gavin Knox, Anastasia Nika, Andrew Hall, Hayley Gooding, Laura Gallagher
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38890-4

Internet

https://doi.org/10.1038/s41598-023-38890-4

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