Multiple particle tracking analysis in isolated nuclei reveals the mechanical phenotype of leukemia cells

Abstract The nucleus is fundamentally composed by lamina and nuclear membranes that enclose the chromatin, nucleoskeletal components and suspending nucleoplasm. The functional connections of this network integrate external stimuli into cell signals, including physical forces to mechanical responses...

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Bibliographic Details
Main Authors: Diego Herráez-Aguilar, Elena Madrazo, Horacio López-Menéndez, Manuel Ramírez, Francisco Monroy, Javier Redondo-Muñoz
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-63682-5