Multiple particle tracking analysis in isolated nuclei reveals the mechanical phenotype of leukemia cells
Abstract The nucleus is fundamentally composed by lamina and nuclear membranes that enclose the chromatin, nucleoskeletal components and suspending nucleoplasm. The functional connections of this network integrate external stimuli into cell signals, including physical forces to mechanical responses...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-63682-5 |