Molecular mechanism of interaction between fatty acid delta 6 desaturase and acyl-CoA by computational prediction

Keypoints The structure of the Δ6 fatty acid desaturase and substrate complex is modeled. The substrate tunnel and key residues of MpFADS6 catalytic activity are determined. The new insights to determine the mechanism of the membrane-bound desaturases.

Bibliographic Details
Main Authors: Jie Cui, Haiqin Chen, Xin Tang, Hao Zhang, Yong Q. Chen, Wei Chen
Format: Article
Language:English
Published: SpringerOpen 2022-06-01
Series:AMB Express
Subjects:
Online Access:https://doi.org/10.1186/s13568-022-01410-0