A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals.

A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals.

A protective vaccine against HIV-1 will likely require the elicitation of a broadly neutralizing antibody (bNAb) response. Although the development of an immunogen that elicits such antibodies remains elusive, a proportion of HIV-1 infected individuals evolve broadly neutralizing serum responses ove...

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Bibliographic Details
Main Authors: Laura M Walker, Melissa D Simek, Frances Priddy, Johannes S Gach, Denise Wagner, Michael B Zwick, Sanjay K Phogat, Pascal Poignard, Dennis R Burton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2916884?pdf=render

Internet

http://europepmc.org/articles/PMC2916884?pdf=render

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