JNC-1043, a Novel Podophyllotoxin Derivative, Exerts Anticancer Drug and Radiosensitizer Effects in Colorectal Cancer Cells

JNC-1043, a Novel Podophyllotoxin Derivative, Exerts Anticancer Drug and Radiosensitizer Effects in Colorectal Cancer Cells

The objective of this study was to determine whether (5S)-5-(4-benzyloxy-3,5-dimethoxy-phenyl)-5,9-dihydro-8H-furo [3’,4’:6,7] naphtho [2,3-d] [1,3]dioxol-6-one (JNC-1043), which is a novel chemical derivative of β-apopicropodophyllin, acts as a novel potential anticancer reagent and radiosensitizer...

Full description

Bibliographic Details
Main Authors: Jin-Hee Kwon, Na-Gyeong Lee, A-Ram Kang, In-Ho Ahn, In-Young Choi, Jie-Young Song, Sang-Gu Hwang, Hong-Duck Um, Jong-Ryoo Choi, Joon Kim, Jong Kuk Park
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
JNC-1043
radiosensitizer
topoisomerase inhibitor
ROS
apoptosis
colorectal cancer
Online Access:https://www.mdpi.com/1420-3049/27/20/7008

Internet

https://www.mdpi.com/1420-3049/27/20/7008

Similar Items