Construction and Verification of a Fibroblast-Related Prognostic Signature Model for Colon Cancer

Construction and Verification of a Fibroblast-Related Prognostic Signature Model for Colon Cancer

Traditionally, cancer-associated fibroblasts (CAFs), an essential component of tumor microenvironment, were exert a crucial part in colon cancer progression. In this study, single-cell RNA-sequencing (scRNA-seq) data from 23 and bulk RNA-seq data from 452 colon cancer patients were extracted from th...

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Bibliographic Details
Main Authors: Zhe Zhao, Wenqi Li, LiMeng Zhu, Bei Xu, Yudong Jiang, Nan Ma, LiQun Liu, Jie Qiu, Min Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
single-cell RNA-sequencing(scRNA-seq)
colon cancer
cancer-associated fibroblasts (CAFs)
immune infiltration
drug sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.908957/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.908957/full

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