Human-umbilical cord matrix mesenchymal cells improved left ventricular contractility independently of infarct size in swine myocardial infarction with reperfusion

BackgroundHuman umbilical cord matrix-mesenchymal stromal cells (hUCM-MSC) have demonstrated beneficial effects in experimental acute myocardial infarction (AMI). Reperfusion injury hampers myocardial recovery in a clinical setting and its management is an unmet need. We investigated the efficacy of...

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Main Authors: Luís Raposo, Rui J. Cerqueira, Sara Leite, Liliana Moreira-Costa, Tiago L. Laundos, Joana O. Miranda, Pedro Mendes-Ferreira, João Almeida Coelho, Rita N. Gomes, Perpétua Pinto-do-Ó, Diana S. Nascimento, André P. Lourenço, Nuno Cardim, Adelino Leite-Moreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1186574/full