Anaplastic lymphoma kinase-special immunity and immunotherapy

Alterations in the anaplastic lymphoma kinase (ALK) gene play a key role in the development of various human tumors, and targeted therapy has transformed the treatment paradigm for these oncogene-driven tumors. However, primary or acquired resistance remains a challenge. ALK gene variants (such as g...

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Bibliographic Details
Main Authors: Ye Guo, Hanfei Guo, Yongfei Zhang, Jiuwei Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.908894/full