C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells

<p>Abstract</p> <p>Background</p> <p>The transcription factor, C/EBPbeta, is a key regulator of growth and differentiation in the mammary gland. There are three different protein isoforms of C/EBPbeta. C/EBPbeta-1 and -2 are transactivators, and differ by only 23 N-term...

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Bibliographic Details
Main Authors: Sealy Linda, Wells Sam, Bundy Linda
Format: Article
Language:English
Published: BMC 2005-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/4/1/43