Faster <i>Cryptococcus</i> Melanization Increases Virulence in Experimental and Human Cryptococcosis

Faster <i>Cryptococcus</i> Melanization Increases Virulence in Experimental and Human Cryptococcosis

<i>Cryptococcus</i> spp. are human pathogens that cause 181,000 deaths per year. In this work, we systematically investigated the virulence attributes of <i>Cryptococcus</i> spp. clinical isolates and correlated them with patient data to better understand cryptococcosis. We c...

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Bibliographic Details
Main Authors: Herdson Renney de Sousa, Getúlio Pereira de Oliveira, Stefânia de Oliveira Frazão, Kaio César de Melo Gorgonha, Camila Pereira Rosa, Emãnuella Melgaço Garcez, Joaquim Lucas, Amabel Fernandes Correia, Waleriano Ferreira de Freitas, Higor Matos Borges, Lucas Gomes de Brito Alves, Hugo Costa Paes, Luciana Trilles, Márcia dos Santos Lazera, Marcus de Melo Teixeira, Vitor Laerte Pinto, Maria Sueli Soares Felipe, Arturo Casadevall, Ildinete Silva-Pereira, Patrícia Albuquerque, André Moraes Nicola
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Journal of Fungi
Subjects:
<i>Cryptococcus neoformans</i>
cryptococcosis
virulence
melanin
capsule
extracellular vesicles
Online Access:https://www.mdpi.com/2309-608X/8/4/393

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https://www.mdpi.com/2309-608X/8/4/393

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