Serum Insufficiency Induces RANKL-Independent Osteoclast Formation during Developing Ischemic ONFH

Blood supply interruption induces hypoxia and reduces serum provision to cause ischemia-induced osteonecrosis, including avascular osteonecrosis of the femoral head (ONFH). Oxygen deficiency (hypoxia) is known to induce different expression patterns in osteoblasts and osteoclasts, which have been ex...

Full description

Bibliographic Details
Main Authors: Yi-min Hsiao, Chih-Chien Hu, Mei-Feng Chen, Chih-Hsiang Chang, Yu-Tien Chiu, Yuhan Chang
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/6/685