GTKO rabbit: A novel animal model for preclinical assessment of decellularized xenogeneic grafts via in situ implantation

Wild type (WT) animals cannot be used to objectively assess the immunogenicity of animal tissue-derived biomaterials when used as recipients due to difference with human in α-Gal expression. The purpose of this study is to compare the differences of immunological responses between the GGTA1 gene-kno...

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Bibliographic Details
Main Authors: Yufeng Mu, Yu Zhang, Lina Wei, Liang Chen, Feng Hao, Anliang Shao, Shuxin Qu, Liming Xu
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422003039