Treatment Strategies for KRAS-Mutated Non-Small-Cell Lung Cancer

Activating mutations in KRAS are highly prevalent in solid tumours and are frequently found in 35% of lung, 45% of colorectal, and up to 90% of pancreatic cancers. Mutated KRAS is a prognostic factor for disease-free survival (DFS) and overall survival (OS) in NSCLC and is associated with a more agg...

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Bibliographic Details
Main Authors: Éabha O’Sullivan, Anna Keogh, Brian Henderson, Stephen P. Finn, Steven G. Gray, Kathy Gately
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/6/1635