HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis

HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis

Abstract Autophagy and pyroptosis of macrophages play important protective or detrimental roles in sepsis. However, the underlying mechanisms remain unclear. High mobility group box protein 1 (HMGB1) is associated with both pyroptosis and autophagy. lipopolysaccharide (LPS) is an important pathogeni...

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Bibliographic Details
Main Authors: Jiawei Shang, Feng Zhao, Yongmei Cao, Feng Ping, Wei Wang, Yingchuan Li
Format: Article
Language:English
Published: BMC 2023-01-01
Series:BMC Molecular and Cell Biology
Subjects:
Lipopolysaccharide
Macrophages
Autophagy
Pyroptosis
HMGB1
Subcellular localization
Online Access:https://doi.org/10.1186/s12860-023-00464-7

Internet

https://doi.org/10.1186/s12860-023-00464-7

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