Deep brain stimulation in the globus pallidus alleviates motor activity defects and abnormal electrical activities of the parafascicular nucleus in parkinsonian rats

Deep brain stimulation in the globus pallidus alleviates motor activity defects and abnormal electrical activities of the parafascicular nucleus in parkinsonian rats

Deep brain stimulation (DBS) is an effective treatment for Parkinson’s disease (PD). The most common sites targeted for DBS in PD are the globus pallidus internal (GPi) and subthalamic nucleus (STN). However, STN-DBS and GPi-DBS have limited improvement in some symptoms and even aggravate disease sy...

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Bibliographic Details
Main Authors: Jinlu Xie, Zheng Chen, Tingting He, Hengya Zhu, Tingyu Chen, Chongbin Liu, Xuyan Fu, Hong Shen, Tao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
deep brain stimulation
globus pallidus
parafascicular nucleus
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1020321/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1020321/full

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