Gut microbes with the gbu genes determine TMAO production from L-carnitine intake and serve as a biomarker for precision nutrition

Gut microbial metabolism of L-carnitine, which leads to the production of detrimental trimethylamine N-oxide (TMAO), offers a plausible link between red meat consumption and cardiovascular risks. Several microbial genes, including cntA/B, the cai operon, and the recently identified gbu gene cluster,...

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Main Authors: Wei-Kai Wu, Yi-Ling Lo, Jian-Ying Chiu, Chia-Lang Hsu, I-Hsuan Lo, Suraphan Panyod, Yu-Chieh Liao, Tina H. T. Chiu, Yu-Tang Yang, Han-Chun Kuo, Hsin-Bai Zou, Yi-Hsun Chen, Hsiao-Li Chuang, Jeffrey J. Y. Yen, Jin-Town Wang, Han-Mo Chiu, Cheng-Chih Hsu, Ching-Hua Kuo, Lee-Yan Sheen, Hsien-Li Kao, Ming-Shiang Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2446374